Navigating fatigue: Strategies for managing fatigue in liver disease

Chronic fatigue, lasting over 6 months, is a primary concern in patients with chronic liver disease and greatly impacts their daily lives^1,2.

Diagnosis of fatigue due to liver diseases³

Fatigue diagnosis in CLD is complicated and requires⁴

Assessment of fatigue in liver disease⁴

Management of fatigue in liver disease⁴

A structured approach TrACE algorithm is employed to manage fatigue in liver disease involving 4 steps:

Treatment of fatigue in liver disease⁵

The treatment of CLD-related fatigue requires a comprehensive strategy that focuses on the patient as a whole.

CONCLUSION
Patients with CLD frequently experience fatigue significantly impacting their day-to-day activities and quality of life. Effective management strategies are crucial to alleviate symptoms and improve overall well-being.

References

1. Kosnik A, Wojcicki M. Fatigue in chronic liver disease patients: prevalence, pathophysiology, and management. Prz Gastroenterol. 2022;17(1):21-27. doi:10.5114/pg.2022.1145943.
2. Gerber LH, Weinstein AA, Mehta R, Younossi ZM. Importance of fatigue and its measurement in chronic liver disease. World J Gastroenterol. 2019;25(28):3669-3683. Doi: 10.3748/wjg.v25.i28.3669.
3. Bhandari K, Kapoor D. Fatigue in Cirrhosis. J Clin Exp Hepatol. Mar-Apr 2022;12(2):617-624. doi:10.1016/j.jceh.2021.08.0284.
4. Swain MG, Jones DEJ. Fatigue in chronic liver disease: New insights and therapeutic approaches. Liver Int. Jan 2019;39(1):6-19. Doi:10.1111/liv.13919.
5. Effiong A, Kumari P. Pharmacotherapies for fatigue in chronic liver disease (CLD): a systematic review and meta-analysis (protocol). Syst Rev. 2018;7(1):28. Published 2018 Feb 14. doi:10.1186/s13643-018-0688-7